Here is a collection of all hotkeys and shortcuts you can use in Minecraft 1.20.1 Java Edition to help with inventory management and general gameplay.
F1 = Hide GUI
F2 = Take Screenshot
F3 = Debug Info (includes coordinates)
F3 + Shift = Toggles Profiler
F3 + A = Reload Chunks
F3 + B = Shows Hitboxes
F3 + C = Manual Crash
F3 + D = Chat History [thanks TehNolz)]
X Load Toolbar Activator key.loadToolbarActivator Press this key + any number, to access any of the 9 saved toolbars.
C Save Toolbar Activator key.saveToolbarActivator Press this key + any number, to save the current toolbar under that number.
F3 + F = Increase Render Distance by 1 [thanks TehNolz]
F3 + F + Shift = Decrease Render Distance by 1 [thanks TehNolz]
F3 + G = Toggle Chunk Borders [thanks TehNolz]
F3 + H = Advanced Item Tooltips (adds detail for most tools, ie the number of hits remaining on a pickaxe)
F3 + N = Toggle Between Spectator & Creative Modes [thanks TehNolz]
F3 + P = Toggles Game Pause (allows for Alt + Tab without having the menu appear)
F3 + Q = Show All F3 Key Combinations [thanks TehNolz]
F3 + S = Reload Sounds and Textures [thanks TehNolz]
F3 + T = Reload all sounds, textures, models and other content that was added/changed by a resource pack [thanks TehNolz]
F5 = Toggle Camera View
F3 + Alt = Shows FPS Graph [thanks 2_40]
Tired of reading? Here's a video we made to go over the rest!
F11 = Toggle Full Screen
1-9 Keys (not numpad) = Quick Move to/from Hotbar
F = Switch Items Between Off Hand and Main Hand [thanks 2_40]
Q = Drop Single Item
Q + Ctrl = Drop Entire Stack of Items
T = Open Chat
L for achievements
/ Open Command
Left Shift = Sneak (allows you to get close to the edge of blocks without falling
Tab = Shows Player List, auto completes commands, usernames etc [thanks 2_40]
Ctrl (or double-tap W) = Sprint
Middle-Click Mouse = Pick Block (will move block you click onto hotbar if it's in your inventory in survival)
Right-Click Mouse (on stack in inventory) = Grabs half of the stack
Hold Right-Click Mouse (in crafting grid/inventory) = Distributes only one of the item held in each slot you mouse over
Hold Left-Click Mouse (in crafting grid/inventory) = Evenly distributes the item held in each slot you mouse over
Left-Click Mouse + Shift (in crafting table) = Crafts as many of item as possible
Double Left-Click Mouse = Grabs all of one item (up to a full stack)
Double Left-Click Mouse + Shift (while hovering over item) = Moves all of the same item from inventory to chest or vise versa)
We will actively update this list to ensure that we have all known shortcuts and hotkeys minecraft has to offer.
